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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXC1
All Species:
0.91
Human Site:
S235
Identified Species:
2.22
UniProt:
Q12948
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12948
NP_001444.2
553
56789
S235
T
E
N
G
T
C
P
S
P
P
Q
P
L
S
P
Chimpanzee
Pan troglodytes
XP_001174718
240
23092
Rhesus Macaque
Macaca mulatta
XP_001119000
442
46184
D143
F
V
K
V
P
R
D
D
K
K
P
G
K
G
S
Dog
Lupus familis
XP_546791
479
51548
E179
D
V
P
K
E
K
E
E
R
A
H
L
K
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61572
553
56935
C235
I
K
T
E
N
G
T
C
P
S
P
P
Q
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990337
528
54812
T198
D
I
K
T
E
N
G
T
A
S
P
P
Q
A
V
Frog
Xenopus laevis
Q9PVZ3
492
53656
K189
K
D
A
T
K
E
D
K
E
R
L
L
K
E
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32027
508
54498
E187
K
R
Q
A
M
M
N
E
K
L
A
E
M
K
P
Honey Bee
Apis mellifera
XP_001121752
495
55049
P186
L
K
R
Q
G
L
V
P
E
K
Q
R
Q
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780709
519
57235
C204
G
D
K
D
D
R
E
C
D
Q
L
R
K
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
79.1
50.2
N.A.
93.4
N.A.
N.A.
N.A.
57.3
69.9
N.A.
N.A.
32.3
31.1
N.A.
35
Protein Similarity:
100
43.2
79.3
60.7
N.A.
95.1
N.A.
N.A.
N.A.
62.5
75.5
N.A.
N.A.
43.2
42.5
N.A.
48.6
P-Site Identity:
100
0
0
6.6
N.A.
13.3
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
0
0
6.6
N.A.
20
N.A.
N.A.
N.A.
20
6.6
N.A.
N.A.
13.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
0
10
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
20
0
0
0
0
0
0
0
% C
% Asp:
20
20
0
10
10
0
20
10
10
0
0
0
0
0
0
% D
% Glu:
0
10
0
10
20
10
20
20
20
0
0
10
0
20
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
10
10
10
0
0
0
0
10
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
20
30
10
10
10
0
10
20
20
0
0
40
10
0
% K
% Leu:
10
0
0
0
0
10
0
0
0
10
20
20
10
0
10
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
10
0
10
10
10
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
10
0
10
0
10
10
20
10
30
30
0
10
30
% P
% Gln:
0
0
10
10
0
0
0
0
0
10
20
0
30
0
20
% Q
% Arg:
0
10
10
0
0
20
0
0
10
10
0
20
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
20
0
0
0
10
10
% S
% Thr:
10
0
10
20
10
0
10
10
0
0
0
0
0
0
0
% T
% Val:
0
20
0
10
0
0
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _